Refine Search
Map
Sort by
$625,000
2026039445 MLS
Rare St. James City opportunity! WATERFRONT OFFICE/SHOP AND 2-BEDROOM APARTMENT ...C-1 zoned 100' x 130' waterfront lot in the heart of the business district, offering a unique combination of commercial, residential, and boating potential. The front portion of the building features office/shop space with tile flooring, 1/2 bath, and ample parking. The rear offers a 2-bedroom, 1-bath apartment with an open living area, equipped kitchen, and sliding glass doors overlooking the canal. A detached 2-car garage includes additional shop/storage space for tools, fishing and boating equipment. Enjoy a spacious backyard, seawall, and 1/2 of a boat basin with direct salt water access to the Gulf. Work from home, operate your business, and enjoy the island lifestyle with easy access to boating, fishing, beaches, and local Island restaurants. A truly versatile waterfront property with endless possibilities!

3269 Stringfellow Rd, St. James City
$?
2026038843 MLS
Key West-style complex with new metal roofs. Neighborhood Commercial zoning for flexible office/medical use. City utilities and quick access to major roads. Fort Myers location near Summerlin Road, between Colonial Blvd and Boy Scout Dr. Ample shared parking on-site. Adjacent to residential and retail amenities. $17.00 PSF + $7.90 CAM = $2,728.63/mth. for the first year. The 1,315± SF suite is fully built-out and ready for immediate occupancy. Designed with a professional layout, it includes three private offices, a conference room, kitchenette, and two restrooms. The space features attractive wood flooring and modern finishes. Convenient for medical or professional office use, with easy access for clients and staff. Lease rate does not include utilities, property expenses or building services

42 Barkley Cir Unit 42-1, Fort Myers
$?
226032826 MLS
STE 104 (2,248± RSF). Available within 90 days of lease execution. Currently operating as an animal clinic. Layout consists of reception, lobby, 2 exam rooms, treatment room, surgery room, x-ray room, utility room, breakroom, office and restroom. Building signage on US-41 available. Professionally managed office / medical office building fronting US-41. Direct access to fiber network. Located at the signalized intersection of US-41 and Woods Edge Parkway. Excess parking.

28901 Trails Edge Blvd, Bonita Springs
$1,150
2026038221 MLS
This multi tenant building is located in Downtown Cape Coral. Enjoy this upstairs unit with, easy access, high ceilings and plenty of natural light. Perfect office space for a small business looking to appear professional in this nice building. This unit is move in ready and features separate office spaces for privacy.

1322 Se 46th Ln, Cape Coral
$1,280
2026037818 MLS
Welcome to this beautifully updated office space in the heart of Downtown Cape Coral! This bright and modern office has everything you need for a comfortable and professional working environment. The space features central air conditioning, a private bathroom, and a kitchenette, providing all the convenience you need throughout the workday. The office has been freshly renovated and painted, creating a clean and welcoming atmosphere. Modern LED ceiling lighting throughout the space provides excellent, energy-efficient illumination. Located in a prime Downtown Cape Coral location, the office is close to restaurants, shops, banks, and many other amenities, making it an ideal location for a business, professional office, or service-based company. The building is 100% occupied.? The office have virtually unlimited parking in the back.

1314 Cape Coral E Pkwy Unit 312, Cape Coral
$1,075,000
2026036572 MLS
Income producing, Mixed-use free-standing building fronting San Carlos Blvd, Fort Myers Beach. Great location. Two story building, upstairs offers 3 apartments, 2 bedroom 2 bath, 1 bedroom 1 bath and 1 bedroom 1 bath Shared launder room with two separate locked storage areas. There are 5 meters, you could add more apartments. 1st level needs refurbished. It operated as retail, Napa Store, Towing office, car rentals and sales. So much potential.

19011 San Carlos Blvd, Fort Myers Beach
$649,999
2026036157 MLS
PRIME SOUTH FORT MYERS COMMERCIAL LOCATION! Excellent opportunity to own a versatile 1,509 SF office/flex space ideally located between Daniels Pkwy and Six Mile Cypress Pkwy, with easy access to I-75 and minutes from Southwest Florida International Airport. The property is near Lee Health Sports Complex, Gulf Coast Medical Center, South Fort Myers High School, and San Carlos Park. Current layout features 3 private offices, reception/waiting area, kitchen, storage, central A/C, and a 12' x 12' overhead roll-up door with forklift access. Interior walls are removable, allowing easy reconfiguration for various business needs. Ideal for office, office/warehouse, flex, light industrial, or storage use, subject to zoning and association requirements. Clean, well-maintained commercial center with 7 parking spaces. HOA is $299/month and includes water, waste service, and exterior maintenance. SELLER FINANCING AVAILABLE: Seller willing to finance $449,999 with $200,000 down, 10% interest, 15-year term. Estimated monthly payment: $4,835. Terms subject to seller approval and final agreement. Great opportunity for an owner-user or investor seeking a flexible commercial property in a strategic South Fort Myers location near major roads, medical facilities, businesses, residential communities, I-75, and the airport.

13861 Plantation Rd Unit 103, Fort Myers
$2,900
226031067 MLS
Move-in ready small office space in the heart of Bonita Springs. This 1,166sf +/- space is comprised of a nice sized lobby/waiting area, built-in reception desk, one private office, conference room, private bathroom, bullpen area, and storage closet. Formerly occupied by Edward Jones financial for over 12 years. Bernwood Courtyard is a lovely enclave of single story office and medical office users - Class A facility with plenty of parking. This space is offered at $2,900/month gross + utilities.

24840 Burnt Pine Dr Unit 3, Bonita Springs
$?
2026035314 MLS
BEAUTIFULLY REMODELED BOUTIQUE SALON | FOR LEASE | FORT MYERS Rare opportunity to lease a beautifully remodeled, turnkey boutique salon in a convenient Fort Myers location. Offered at $3,500 per month, this professionally designed space features a bright, modern aesthetic and is ideal for an established salon operator or beauty professional looking to open or expand without the expense and hassle of a full build-out. The salon features a welcoming reception area, retail display shelving, multiple styling stations, shampoo bowls, and an open, functional floor plan. Additional private areas offer flexibility for esthetics, massage, nails, lashes, makeup, and other beauty or wellness services. The space is partially furnished, with shampoo bowls and select furnishings included, providing an excellent foundation to begin operations quickly. Large storefront windows provide abundant natural light and visibility, while convenient parking offers easy access for clients and staff. Contemporary lighting, custom décor, and distinctive finishes create an inviting, upscale atmosphere and memorable client experience. This is a unique opportunity to lease a beautifully appointed boutique salon in Fort Myers without starting from a traditional commercial shell. Shampoo bowls and select furnishings are included. Salon business, additional equipment, supplies, and personal property are not included unless otherwise agreed. Opportunities to lease a fully built-out salon space like this are hard to find. Schedule your private showing today and see firsthand everything this beautiful space has to offer. Bring your vision, your clients, and your business—this salon is ready for its next chapter!

5235 Ramsey Way Unit D1, Fort Myers
$?
226030018 MLS
Fully furnished 2nd floor office space in the United Bank building. Fully furnished office space featuring reception area, eight private offices, conference room, two private restrooms, breakroom, copier room and a dedicated storage/IT room. Private elevator access. 34 parking spaces. Lease Rate: $18.75 PSF + NNN (est. $6.18 PSF).

14241 Metro Pkwy, Fort Myers
$?
2026034899 MLS
Great centralized location for commercial uses just off US 41 Cleveland Ave. and Colonial Blvd. across from Edison Mall. One large unit 1,798 sq. ft. previously used as a church with stage, 2 baths, plus smaller office or classrooms. Two units 1,044 sq. ft. each with front office and open areas, rooms, and bathrooms can be combined for one large unit. One smaller unit 754 sq. ft, with bathroom access. One truck parking/storage unit with loading dock 986 sq. ft.. Three storage units with overhead doors side by side totalling 810 sq. ft. All units include water. Storage units also include electricity.

39 Mildred Dr, Fort Myers
$2,750
2026034802 MLS
This 1,186 sf first floor office is located in Southeast Cape Coral along 47th Street and Vincennes Blvd. corridor. Available September 1st this unit includes an open lobby/ reception area with vaulted ceilings, 3 private offices, conference room, kitchenet and a large storage closet/ file station. Windows face south overlooking the parking lot. This are offers on-street parking and has covenient access from Del Prado Blvd. Coronado and Vincennes.

1325 Se 47th St Unit A, Cape Coral
$?
2026033992 MLS
Fully built-out professional office suite available for sublease in a prime location. The current layout offers 8 private offices, including 3 oversized executive offices with solid doors and 5 additional private offices, plus a dedicated conference room and a full kitchen with quartz counters, beverage fridge, and microwave. Modern finishes throughout with wood accent walls, upgraded lighting, and large windows with great natural light. Please note: the space is shown furnished, but no furniture or fixtures convey. This includes the glass office partitions, which will be removed prior to occupancy. Ideal for a professional firm, real estate office, law practice, financial services, or medical admin use. Approximately 2,109 SQFT. Below-market rate for the area. Easy access to [main road/corridor], with ample parking. Schedule your showing today.

2503 Del Prado Blvd Unit 510, Cape Coral
$1,239,000
2026029157 MLS
Turnkey income opportunity in a fast-growing East Fort Myers corridor near the Verandah and Riverhall. This ±4,500 SF building is 100% occupied by five established tenants, delivering stabilized, day-one cash flow. Current tenants include: State Farm, Nail Salon, Realty office, Salon Spa, and a Legal firm. Fronting Palm Beach Boulevard (SR 80) — a major arterial road carrying roughly 35,000+ vehicles per day — the property offers strong visibility, direct highway frontage, and easy access. Meticulously maintained, the property features a new roof and updated interiors — a clean, low-maintenance asset ready to perform. A diversified rent roll and continued growth along the SR 80 corridor make this a rare combination of stable income and long-term upside. Opportunities like this don't last.

13102 Palm Beach Blvd, Fort Myers
$659,000
2026033611 MLS
RARE FREESTANDING OWNER-USER OPPORTUNITY IN CENTRAL FORT MYERS. Freshly relaunched and presented in pristine, move-in-ready condition, 2080 Collier Ave offers approximately 2,400 SF under air with an exceptional combination of professional space, flexibility and approximately 25 paved parking spaces. The thoughtfully designed layout features 4 spacious private offices, an additional office/flex room, conference room, professional reception/lobby, approximately 1,000 SF open multipurpose area, full kitchenette with stone countertops and oversized ADA-compliant restrooms. Updated flooring, LED lighting, fresh finishes and a newer 2023 roof make this an outstanding opportunity for an owner-user ready to occupy without taking on a major renovation. Ideal for medical, chiropractic, therapy, wellness, med-spa, legal, insurance, financial services, adult day services, education, training, professional services or corporate headquarters, subject to applicable zoning and use approvals. The large open flex space provides tremendous versatility for training, group activities, classrooms, therapy, meetings or future customization. Centrally positioned near US-41 with convenient access to Downtown Fort Myers, Colonial Blvd, Lee Health and major business corridors. The combination of a freestanding building, abundant dedicated parking and adaptable interior space is increasingly difficult to duplicate in this price range. Why continue leasing when you can own the building your business operates from and build equity in your own real estate? Cash and conventional financing welcome. Seller financing may be considered for a qualified buyer. Pristine and ready for immediate occupancy. Schedule your private showing today.

2080 Collier Ave, Fort Myers
$3,600,000
226028552 MLS
6200 Whiskey Creek Drive offers investors the opportunity to acquire an 11,833 square-foot, single-tenant, net leased office building in Fort Myers, Florida. Built in 2005, the property is defined as Lot 4 within Oak Hammock at Whiskey Creek and is 100% leased to Bowman Consulting Group, Ltd., Inc., a national engineering, surveying, infrastructure design, and consulting firm with offices throughout Florida and across the U.S. The building is used for engineering, surveying, and general office purposes, supporting the tenant’s core operational needs. The offering provides a clear income profile supported by a triple net lease structure and limited landlord responsibilities. The current lease term extends through October 31, 2031, with approximately 5.5 years of remaining term. The lease includes 3.0% annual base rent increases through the current term and 2 remaining five-year renewal options, providing investors with scheduled rent growth and future extension optionality. Well positioned within Fort Myers in Lee County, a key Southwest Florida market supported by tourism, transportation, logistics, and healthcare access. The surrounding area offers proximity to retail corridors, national retailers, nearby healthcare services, and regional connectivity via Southwest Florida International Airport, located within an approximately 30-minute drive.

6200 Whiskey Creek Dr, Fort Myers
$375,000
226028496 MLS
Ideally positioned along the highly sought-after Alico Road corridor in South Fort Myers, 17030 Alico Road benefits from exceptional connectivity and proximity to some of Southwest Florida's most significant commercial, residential, and employment hubs. The property is located just east of the interchange with Interstate 75 and minutes from Southwest Florida International Airport, providing convenient regional and national access. The site is surrounded by major amenities, including Gulf Coast Town Center, featuring over 100 retail stores, restaurants, entertainment venues, and national retailers, as well as nearby Florida Gulf Coast University and numerous hotels, office campuses, industrial parks, and rapidly expanding residential communities. Its strategic location offers direct access to major transportation corridors including Alico Road (CR 840), Ben Hill Griffin Parkway, and Interstate 75, positioning the property at the center of one of Southwest Florida's fastest-growing mixed-use and logistics corridors.

17030 Alico Commerce Ct Unit 303, Fort Myers
$340,000
226028483 MLS
Ideally positioned along the highly sought-after Alico Road corridor in South Fort Myers, 17030 Alico Road benefits from exceptional connectivity and proximity to some of Southwest Florida's most significant commercial, residential, and employment hubs. The property is located just east of the interchange with Interstate 75 and minutes from Southwest Florida International Airport, providing convenient regional and national access. The site is surrounded by major amenities, including Gulf Coast Town Center, featuring over 100 retail stores, restaurants, entertainment venues, and national retailers, as well as nearby Florida Gulf Coast University and numerous hotels, office campuses, industrial parks, and rapidly expanding residential communities. Its strategic location offers direct access to major transportation corridors including Alico Road (CR 840), Ben Hill Griffin Parkway, and Interstate 75, positioning the property at the center of one of Southwest Florida's fastest-growing mixed-use and logistics corridors.

17030 Alico Commerce Ct Unit 301, Fort Myers
$350,000
226028486 MLS
Ideally positioned along the highly sought-after Alico Road corridor in South Fort Myers, 17030 Alico Road benefits from exceptional connectivity and proximity to some of Southwest Florida's most significant commercial, residential, and employment hubs. The property is located just east of the interchange with Interstate 75 and minutes from Southwest Florida International Airport, providing convenient regional and national access. The site is surrounded by major amenities, including Gulf Coast Town Center, featuring over 100 retail stores, restaurants, entertainment venues, and national retailers, as well as nearby Florida Gulf Coast University and numerous hotels, office campuses, industrial parks, and rapidly expanding residential communities. Its strategic location offers direct access to major transportation corridors including Alico Road (CR 840), Ben Hill Griffin Parkway, and Interstate 75, positioning the property at the center of one of Southwest Florida's fastest-growing mixed-use and logistics corridors.

17030 Alico Commerce Ct Unit 3200, Fort Myers
$295,000
226028308 MLS
Experience the timeless appeal of this 1,553 SF office building located at 2023 Jeffcott St in Fort Myers, FL. Originally constructed in 1939 and revitalized in 2026, this property seamlessly blends historic charm with modern functionality. Zoned CI, it offers a versatile space ideal for various office or co-working configurations. The strategic location within the City of Fort Myers area ensures excellent accessibility from Cleveland Ave (US 41). With its rich history, recent updates, and prime zoning, this property presents an exceptional opportunity for office users looking to establish or expand their presence in this vibrant market. Priced very competitively as one of very few small free-standing office properties in the area. Sold as vacant for immediate occupancy.

2023 Jeffcott St, Fort Myers
$1,000
2026017927 MLS
2nd Floor Office Building with 2 rooms overlooking Marinatown Yacht Harbor. $1000 per month plus electric. Looking for a minimum or 1 year, but would consider a long term lease.

3436 Marinatown Ln, North Fort Myers
$4,500
2026031499 MLS
AVAILABLE SEP. 15! Fully Remodeled 500 SF corner office suite in Sea Grape Plaza, commanding a high-visibility position right on Estero Blvd, Fort Myers Beach's main road. Natural light and Gulf water views, while your business gets front-and-center exposure to the steady stream of beach traffic passing by daily. Move-in ready with open on-site parking for you and your clients. This location puts your business right where residents and visitors already are. 12-month lease at $4,500/mo (Apr–Dec); $5,000/mo Jan–Mar (high season). A rare opportunity to plant your business on the beach's busiest corridor.

2801 Estero Blvd Unit A, Fort Myers Beach
$1,400
2026030892 MLS
FOR LEASE! Ideally located at a signalized intersection on Colonial Boulevard and Deleon St. Traffic 54,000 Cars per day Near US41 / Cleveland Ave 2 story, it can be converted as separated properties, downstairs and upstairs, with 2 different entrances. Excellent exposure Signage opportunity on busy Colonial Boulevard

1705 Colonial Blvd Unit D2, Fort Myers
$2,495,000
2026026549 MLS
A rare opportunity to secure one of the most visible and strategically positioned commercial assemblages on Sanibel Island's iconic Periwinkle Way corridor. Offering approximately 150 feet of prime frontage along the island's primary commercial artery, 1444 and 1446 Periwinkle Way present a unique chance to shape the future of one of Sanibel's most recognizable locations. The combined offering includes three existing structures spread across two commercial parcels, creating exceptional flexibility for investors, owner-users, developers, retailers, restaurants, garden concepts, professional offices, wellness destinations, galleries, showrooms, mixed-use redevelopment, and countless other possibilities. Imagine revitalizing the existing buildings into a collection of charming Old Florida commercial spaces, creating an inviting courtyard-style destination, or starting fresh with a completely new vision designed to maximize visibility, parking, and customer experience along one of the island's highest traffic corridors. Opportunities of this scale, frontage, and flexibility rarely become available on Sanibel, where commercial land has historically remained tightly held for decades. There has never been a more exciting time to invest in Sanibel's future. The island is experiencing a remarkable rebirth as businesses rebuild, reinvent, and reimagine what comes next. New concepts, new architecture, and new energy are returning to the Sanctuary Island, creating an environment unlike any other point in recent history. As long-established properties transition to new ownership and new ideas, buyers have a rare opportunity to become part of the next chapter of Sanibel's commercial evolution. Adjacent to the Bailey Homestead Preserve and Garden Center and neighboring the lands of SCCF, this highly visible location combines natural beauty with exceptional exposure and accessibility. Whether your vision is restoration, redevelopment, investment, or creating an entirely new island destination, 1444 and 1446 Periwinkle Way offer the location, flexibility, and visibility to bring that vision to life. Prime commercial frontage. Exceptional visibility. Endless possibilities. The future of Sanibel is being written now and this is your opportunity to help shape it.

1446 Periwinkle Way, Sanibel
$1,000,000
2026029913 MLS
Centrally located in World Plaza, this 3,264± SF professional office property consists of two adjoining office suites, addressed as 12611 and 12613 New Brittany Blvd. The flexible layout includes multiple private offices, conference space, a kitchen, reception area, and a spacious multifunction room with cubicle workspace. Ideal for an owner-user, investor, or combination of both, with the potential to occupy one suite while generating rental income from the other.

12611/613 New Brittany Blvd, Fort Myers
$1,495,000
2026030098 MLS
Located in the Mid Metro Industrial Park, between Metro Pkwy and Plantation Rd. Base SF: 3,864± SF | Garages: 2,072± SF | Porch Area 489± SF | Total SF: 6,425± SF | 12 Offices, 2 Kitchen Areas, 2 Bathrooms, 3 Garages, Fenced in area (chain link) Positioned in the heart of Fort Myers’ industrial corridor, 6241 Arc Way offers an adaptable environment for manufacturing, warehouse, or logistics operations. The property provides convenient access to major transportation routes, including I-75 and US-41, ensuring efficient regional connectivity. Its location places businesses within proximity to Southwest Florida International Airport and key commercial hubs, making it an advantageous site for distribution or service activities.

6241 Arc Way, Fort Myers
$1,072,000
2026029707 MLS
3,634 two unit building in good condition located in CRA district. The property is zoned SC which is a very flexible zoning. The property has been previously used as an insurance office, Real Estate office, Deli, and now has one unit being used a a Bakery. The Bakery tenant's lease ends at the end of August 2026. They would like to stay on. The property can be used as three units. Excellent opportunity for owner occupant or investors. The property is in good condition and is being sold AS IS.

1615 Se 47th Ter, Cape Coral
$585
2026029235 MLS
Beautiful Office... Executive Suites of Cape Coral, GREAT WAY TO CONTROL YOUR BUSINESS COST. Single Offices Include: Internet, Conference Room Time, Mail and Package Services to Your Office, full use of business center, Wi-Fi, Cyber Cafe, Lobby Display of Your Company. 24/7 Access. Professional Business - Also Available Virtual Offices from @129/month, lots of Parking, Same Building as USPS Post Office SW Cape Coral CPU and FEDEX. Copy/Fax Available, Notary Services, Great Location Near Intersection of Cape Coral Parkway and Chiquita Blvd, Seconds from Cape Harbour Marina/Shops. Lots of Banks Restaurants. always available to upgrade from virtual to Private offices or larger/multiple offices, PRICES INCLUDE WATER, ELECTRICITY, CAM, MAINTENCE. Conference Rooms available for rent by 1/2 day or full day.

4706 Chiquita S Blvd Unit 200, Cape Coral
$629,000
226025383 MLS
Excellent Location with Easy Access to Central Fort Myers and Cape Coral; 59,400 Cars Per Day 2025 (TCDS) Lee County; 9 Parking Spaces, Plus 4 Shared; Lighted Sign

1625 Colonial Blvd, Fort Myers
$2,989,000
2026018701 MLS
Exceptional mixed-use investment opportunity in the heart of Sanibel Island’s Town Center Commercial District.Situated on highly traveled Palm Ridge Road, this unique property offers outstanding visibility, a consistent incomehistory, and the rare combination of commercial frontage with scenic lake views and tropical wildlife surroundings.The property consists of three buildings featuring seven remodeled residential apartments and six establishedcommercial units, along with two separate garage/storage rentals providing additional income. Several residentialunits enjoy peaceful lake views, enhancing tenant appeal. The residential component includes seven bedrooms andseven bathrooms, while the 6 commercial spaces are equipped with eight half-bathrooms, allowing for flexibleconfigurations suited to professional, retail, service, or live-work uses. This asset has a proven track record as anincome-producing property and has previously been utilized by the City of Sanibel, underscoring its versatility andlong-term value within the community. Ideally positioned with convenient access to Captiva and all areas of Sanibel,the property is located within one of the island’s most established and desirable commercial corridors. Occupancyhas remained consistently strong, with all commercial units currently leased and all but one residential unit occupied.Detailed rent rolls and financials are available to qualified buyers. For investors seeking to be part of the early stagesof Sanibel and Captiva’s resurgence, this property offers a rare opportunity to acquire a stabilized, income-producingasset while positioning for the next chapter of growth, revitalization, and long-term appreciation in one of SouthwestFlorida’s most iconic island markets.

2430 Palm Ridge Rd Unit 2426, Sanibel